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Abstract                 Volume:4  Issue-1  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Approaches on Nano-based drug delivery for Alzheimer s Disease: Methods for Diagnosis, Pharmacology and Safety matter
Rakesh Kumar Singh*
Department of Chemistry, University of Allahabad, Allahabad- 211002, India
*Corresponding author
Abstract:

The large number of people diagnosed with a neurodegenerative disorder i.e. Alzheimer s disease (ADs), a increasing rapidly. AD is the most common form of dementia worldwide, affecting more than more than 35 million people. It is characterized by memory dysfunction, spatial and temporal orientation, and loss of lexical access. Although clinical development of drugs for the symptomatic and disease modifying treatment of AD. A large number of drugs with different mode of targets and their mechanism were investigated. The targeted nano based drug (eg. Nanoparticles: NPs) delivery to the central nervous system (CNS), for diagnosis and treatment of AD, due to limitations posed by the restrictive blood brain barrier (BBB). This review literature provides a concise approach into the current and future applications of nano based medicine for the treatment of ADs, besides reviewing and discussing the literature on the drug delivery, their diagnosis and treatment for safety point of view in Alzheimer s.

Keywords: Alzheimer s disease, Nanoparticles, Nanotechnology, Polyphenols, MRI
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How to cite this article:

Rakesh Kumar Singh. 2016. Approaches on Nano-based drug delivery for Alzheimer s Disease: Methods for Diagnosis, Pharmacology and Safety matter.Int.J.Curr.Res.Aca.Rev. 4(1): 132-145
doi: http://dx.doi.org/10.20546/ijcrar.2016.401.012