Abstract            Volume:12  Issue-7  Year-2024         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Salmonella, whose serovars have a broad host range, can infect a wide variety of animals, humans and contaminate environment. Thus, significant pathogen in the one health aspect of the globe. From the two major species of the bacteria, Salmonella enterica and Salmonella bongori, the former one interplays among animal, human and environment becoming food-borne infection of public health and economic significance. Humans acquire infection mostly through feco-oral route and rarely through direct contact. Diarrhea, enteric fever, and abdominal pain are the common clinical manifestations followed by death with extreme cases. Costs related to disease surveillance; and prevention, control and treatment are the possible economic impacts. Worldwide increment of single and multi-drug resistant strains of the microorganism is the most alarming issue of the date. According to current updates in the reviews and research works, the issue is particularly severe in developing nations such as Ethiopia because there are barriers to maintaining the best possible hygienic food handling procedures and irrational drug usage habits. Both conventional (bacteriological culturing, biochemical tests) and advanced (immunological and molecular based) diagnostic approaches are being used to identify the pathogen and to ascertain the anti-microbial susceptibility profile. Biosecurity is the main approach of Salmonella prevention. Treatment is possible with antibiotics. Vaccines are also being utilized for some strains of bacteria. Therefore, this paper is intended for reviewing overall current status of Salmonella in humans and animals, concurrently serving as insights for researchers, policy makers and academicians as well. More will be expected from developing world like Ethiopia regarding implementation of detailed investigation aligned with possible corrective actions.

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