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INDEXED IN INDEX COPERNICUS - ICI Journals Master List 2016 - IJCRAR--ICV 2016: 81.15 For more details click here

Abstract                 Volume:4  Issue-7  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
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Anti-Asthmatic, Anti-Inflammatory and Antioxidant Activity of Ethanolic and Hot Water Extract of the Rhizomes of the Plant Alpinia calcarata
Mathew George, Lincy Joseph, K. Sujith and H. Hafees*
Pushpagiri College of Pharmacy, Tiruvalla, Kerala, India 
*Corresponding author
Abstract:

The aim of the paper is to evaluate the anti-asthmatic, anti-inflammatory and anti-oxidant activity of the plant Alpinia calcarata rhizomes. In vivo anti-asthamtic studies are done by histamine induced bronchoconstriction in guinea pigs and also done by milk induced leukocytosis and eosinophilia. The anti-inflammatory studies are done by protein denaturation and rabbit red blood cell membrane stabilization method. Anti-oxidant studies are done by hydrogen peroxide scavenging and reducing power assay. The ethanolic and hot water extract of the plant rhizomes are used for the study. Primary phytochemical screening of the ethanolic extract plant revealed the presence of carbohydrate, reducing sugar, alkaloid, flavonoids and phenolic compounds. The hot water extract of the plant rhizomes revealed the presence the alkaloid, flavonoid, carbohydrate and phenolic compound. Alpinia calcarata Roscoe (Family: Zingiberaceae), it is a rhizomatous perennialherb, which is commonly used in the traditional medicinal systems in Sri Lanka. Alpinia calcarata is cultivated in tropical countries, including india, Srilanka and Malaysia. Experimentally, rhizomes of Alpinia calcarata are shown to possess antibacterial, antifungal, anthelmintic, antinociceptive, anti-inflammatory, antioxidant, aphrodisiac, gastro protective, and antidiabetic activities.

Keywords: Alpinia calcarata,anti-asthmatic,anti-inflammatory,anti-oxidant.
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How to cite this article:

Mathew George, Lincy Joseph, K. Sujith and H. Hafees. 2016. Anti-Asthmatic, Anti-Inflammatory and Antioxidant Activity of Ethanolic and Hot Water Extract of the Rhizomes of the Plant Alpinia calcarata.Int.J.Curr.Res.Aca.Rev. 4(7): 13-25
doi: http://dx.doi.org/10.20546/ijcrar.2016.407.002