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Abstract                 Volume:4  Issue-7  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Evaluation of Clinical Outcome, Drug Utilization and Effect on Liver Enzymes of Anti-epileptics in Epileptic Patients
Mathew George1, Lincy Joseph2, Robert Mathew3 and Preethi Christina Jose4*
1Department of Pharmacology, Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
2Department of Pharmaceutical Chemistry, Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
3Department of Neurology, Pushpagiri College of pharmacy, Thiruvalla, Kerala, India
4Department of Pharmacy Practice, Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
*Corresponding author
Abstract:

Anti-epileptic drugs of various classifications are used to treat different types of seizures. A prospective experimental study is done in 50 epilepsy patients taking atleast 1 anti-epileptic drug in a tertiary care hospital, Kerala, India. The objective of the study is to determine the clinical outcome and drug utilization of anti-epileptics along with the effect of anti-epileptics on serum liver enzymes such as ALP, AST and ALP. Clinical outcome of the patients were obtained using determining the seizure control obtained by the patients. Drug utilization is determined using prescription analysis. Effect in liver enzymes is evaluated using collecting residual blood sample of the patients and determined using semi-auto analyzer and colorimetry.

Keywords: ALT,AST ALP,Seizure Semi-auto analyzer,Colorimetry
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How to cite this article:

Mathew George, Lincy Joseph, Robert Mathew and Preethi Christina Jose. 2016. Evaluation of Clinical Outcome, Drug Utilization and Effect on Liver Enzymes of Anti-epileptics in Epileptic PatientsInt.J.Curr.Res.Aca.Rev. 4(7): 32-37
doi: http://dx.doi.org/10.20546/ijcrar.2016.407.004