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INDEXED IN INDEX COPERNICUS - ICI Journals Master List 2016 - IJCRAR--ICV 2016: 81.15 For more details click here

Abstract                 Volume:4  Issue-7  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Evaluation of Rise in Creatinine in Concomitant Use of Angiotensin Receptor Blockers and Mineralocortioid Receptor Antagonist
Mathew George1, Lincy Joseph2, K.Venugopal3 and Aneeta Anna Abraham3*
1Department of Pharmacology, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India
2Department of Chemistry, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India
3HOD of Cardiology, Pushpagiri Medical College, Thiruvalla, 689107, Kerala, India
4Department of Pharmacy Practice, Pushpagiri College of Pharmacy, Thiruvalla-689107, Kerala, India
*Corresponding author
Abstract:

Cardiovascular diseases are  common and costly medical condition.     Nowadays, combination of angiotensin receptor blockers (ARB) with aldosterone receptor blocker is used to treat patients with heart failure or hypertension. Angiotensin II receptor blockers (ARBs) are an alternative for patients who cannot tolerate angiotensin converting enzyme inhibitors because of their cost and side effects (e.g., cough). Unfortunately these drugs may lead to increase in morbidity and mortality dependent on severe hyperkalemia. The review  aims to evaluate the therapeutics and demographic features of patients with hyperkalemia. These cases revealed, close monitoring of blood chemistry is mandatory after starting spironolactone.CHF patients taking angiotensin receptor blocker and spironolactone were taken and their effect of serum potassium were considered.   

Keywords: Coronary artery disease,Hyperkalemia,Spironolactone,Angiotensin Receptor Blocker
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How to cite this article:

Mathew George, Lincy Joseph, K.Venugopal and Aneeta Anna Abraham. 2016. Evaluation of Rise in Creatinine in Concomitant Use of Angiotensin Receptor Blockers and Mineralocortioid Receptor Antagonist.Int.J.Curr.Res.Aca.Rev. 4(7): 38-43
doi: http://dx.doi.org/10.20546/ijcrar.2016.407.005