Abstract            Volume:4  Issue-9  Year-2016         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

Pemphigus is a group of potentially life-threatening autoimmune diseases characterized by cutaneous and/or mucosal blistering. Pemphigus vulgaris is the most common variant and is characterized by circulating IgG antibodies directed against desmoglein 3 with about half the patients also having desmoglein 1 autoantibodies. Involvement of the oral mucosa is common and in most cases precedes skin lesions. Most patients are initially misdiagnosed and improperly treated for months or even years. Dental professionals must be sufficiently familiar with the clinical manifestations of Pemphigus vulgaris to ensure early diagnosis and treatment, since this in turn determines the prognosis and course of the disease. Here we report a case series of 3 Pemphigus vulgaris cases with preceeding oral manifestations before skin lesions along with successful treatment with steroids as well as steroid sparing therapies.

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