IJCRAR is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCRAR Articles.

Abstract                 Volume:5  Issue-5  Year-2017          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Correlation between Right to Left Ventricular Activation Delay with Paced QRS Duration in Cardiac Resynchronization Therapy
Fariborz Akbarzadeh*
Madani Heart Hospital, Tabriz University of Medical Sciences, Postal code: 51666, Iran
*Corresponding author
Abstract:

Cardiac resynchronization therapy (CRT) is an effective treatment in advanced heart failure (HF). However, almost one third of patients fail to respond to this therapy. We aimed to evaluate the correlation between intrinsic right ventricular (RV) and left ventricular electrogram delay (EGM delay) and corresponding paced QRS duration with narrowing of QRS (delta QRS) after simultaneous biventricular pacing (simul QRS). Fifty-seven consecutive patients who underwent CRT implantation between January 2014 and January 2015 were enrolled. Intrinsic EGM delay, RV only, LV50 pacing QRS width and simul QRS duration were evaluated in 51 surviving patient at 6 months follow-up visit to evaluate the relationship between baseline EGM delay and delta QRS in these different pacing modes and assess its impact on response to CRT. Forty patients (78.4%) were defined as responder. Difference in EGM delay between responder and non-responder patients wasn’t significant (69± 36 and 53 ± 37 msec respectively). Correlation between intrinsic delta EGM and simul QRS was not significant in responder and non-responders. Simul QRS showed significant correlation with RV only and LV50 pacing QRS in responders (correlation coefficient: 0.49 and 0.35 respectively). Simul QRS showed significant correlation with RV only and LV50 pacing but not intrinsic QRS duration. These findings indicate that intrinsic EGM delay does not have a strong correlation with QRS narrowing in simul QRS, RV only and LV50 paced methodsin patients with implanted CRT at 6-month follow-up.

Keywords: Heart failure, Electrogram delay, QRS duration.
Download this article as Download

How to cite this article:

Fariborz Akbarzadeh. 2017. Correlation between Right to Left Ventricular Activation Delay with Paced QRS Duration in Cardiac Resynchronization Therapy.Int.J.Curr.Res.Aca.Rev. 5(5): 1-7
doi: https://doi.org/10.20546/ijcrar.2017.505.001