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International Journal of Current Research and Academic Review-e-iSSN - 2347 - 3215

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Abstract                 Volume:5  Issue-9  Year-2017          Original Research Articles

Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
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In vitro Antibacterial Activity of Clausena dentata (Willd.) M. Roem Leaf extracts Against Opportunistic Bacterial Pathogens of HIV/AIDS Patients
A. Freeda Rose1, S. R. Senthil Kumar2 and T. Francis Xavier2
1Department of Botany, Holy Cross College, Tiruchirappalli – 620 002, Tamil Nadu, India
2Department of Botany, St. Joseph’s College, Tiruchirappalli – 620 002, Tamil Nadu, India
*Corresponding author

Human Immunodeficiency Virus (HIV) is one of the major threats to mankind. HIV infection is a global pandemic with numerous cases reported from many countries. The major threat to their life is not by the virus but due to these opportunistic pathogens and associated complications Infections induced by pathogenic bacteria are recognized as emerging threat to HIV/AIDS patients. Clausena dentata is a small tree belonging to the family Rutaceae with medicinal, nutritive value and volatile oils of four furanoid terpenic compounds, α-clausenan, rosefuran (γ-clausenan) and diclausenans A.In the present study, antibacterial activity of the ethanol, ethylacetate, chloroform, petroleum and acetone extracts of Clausena dentata leaf were tested against ten opportunistic bacteria isolated from the HIV/AIDS patients of Thuraiyur region of Tiruchirappalli District. Among the various solvent extracts tested, the ethanol extract showed significant antibacterial activity against most of the test bacteria. The zones of inhibition were higher in the case of Staphylococcus hominis and Enterobacter faecalis Staphylococcus haemolyticus and Klebsiella pneumoniae

Keywords: HIV/AIDS, Clausena dentata, Rutaceae, Inhibition, Antibacterial
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How to cite this article:

Freeda Rose A., S. R. Senthil Kumar and Francis Xavier T. 2017. In vitro Antibacterial Activity of Clausena dentata (Willd.) M. Roem Leaf extracts Against Opportunistic Bacterial Pathogens of HIV/AIDS Patients.Int.J.Curr.Res.Aca.Rev. 5(9): 60-65
doi: https://doi.org/10.20546/ijcrar.2017.509.009