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Abstract                 Volume:5  Issue-11  Year-2017          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
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Total Phenolic Content in the petals and Oral Acute Toxicity of gossypitrin on Wistar Rats
José Gonzalez1*, Armando Cuéllar1, Dayné Franco2, Max Monan3, Enmanuel Nossin3 and Frantz Françoise-Haugrin3
1Department of Pharmacy, Faculty of Pharmacy and Foods, Havana University, Havana 10400, Cuba
2Centro de Investigaciones Apicolas, La Habana, Cuba
3ARVARNAM, Martinica 97220, France
*Corresponding author
Abstract:

Talipariti elatum Sw. (Fryxell) Malvaceae is a quite attractive tree with its straight trunk, broad green leaves, and hibiscus-like flowers. This medicinal plant is use in various traditional medicine therapeutic applications in Cuba, especially in treatment of bronchial asthma and flu. From ethanolic and toluene extracts of the flowers our research group have characterized more than 50 different chemical compounds as secondary metabolites. One of them, gossypitrin, a glucoside flavonoid isolated and purified from ethanolic extract of the petals had been reported as antibacterial and antifungal and to possess a remarkable antioxidant activity against a lot of amount of different ROS and RNS. Here, in our study, we realized the determination of total phenolic content from the total ethanolic extract using the petals of the flowers and the measurements of the oral acute toxicity of the main flavonoid in the petals of the flowers of T. elatum.

Keywords: Talipariti, Petals, Phenolic content, Oral acute toxicity, Gossypitrin.
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How to cite this article:

José Gonzalez, Armando Cuéllar, Dayné Franco, Max Monan, Enmanuel Nossin and Frantz Françoise-Haugrin. 2017. Total Phenolic Content in the petals and Oral Acute Toxicity of gossypitrin on Wistar Rats.Int.J.Curr.Res.Aca.Rev. 5(11): 53-57
doi: https://doi.org/10.20546/ijcrar.2017.511.010