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Abstract                 Volume:4  Issue-2  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
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A Study on Gamma Glutamyl transferase (GGT) in Non ST Elevation Acute Coronary Syndrome (NSTE-ACS) and its correlation with Angiographic severity and cardiac events
V.Magesh1*, B. Sasi Kumar2 and P. Arunachalam3
1Assistant Professor, Department of Cardiology, Meenakshi Medical College and Research Institute, Kanchipuram-631552, Tamil Nadu, India
2Associate Professor, Department of Cardiology, Meenakshi Medical College and Research Institute, Kanchipuram-631552, Tamil Nadu, India
3Professor and Head, Department of Cardiology, Meenakshi Medical College and Research Institute, Kanchipuram-631552, Tamil Nadu, India
*Corresponding author
Abstract:

The purpose of this study is to investigate the diagnostic value of Gamma Glutamyl transferase (GGT) in Non ST Elevation Acute Coronary Syndrome (NSTE-ACS) and its correlation with Angiographic severity and cardiac events.  Coronary Artery Disease which is one of the leading causes of mortality and morbidity all over the world, has reached epidemic proportions worldwide recently in both Developed as well as Developing Countries. Coronary artery disease causes approximately 9.4% of total deaths  in less developed countries and 16.3% of all deaths in well developed countries.  Non ST Elevation Acute Coronary Syndrome and its Angiographic severity and cardiac events was studied in three groups depends on ACS Significant Stenosis and ACS non significant stenosis.    In all three groups, the levels of Gamma Glutamyl Transferase enzyme  in Non ST Elevation Acute Coronary Syndrome patients (both Unstable AnginaUA and NonST Elevation Myocardial Infarction NSTEMI) who were undergoing coronary angiogram and Control population of effort angina patients with normal coronary arteries by evaluation of atherosclerotic load.  The serum levels of Median GGT values were significantly elevated in ACS patients with significant angiographic stenosis is in comparison with ACS without significant stenosis Serum GGT is an easily available, cost effective and simple biomarker marker, its routine measurement on admission may be helpful for identification of high-risk patients in clinical practice.

Keywords: Gamma Glutamyl Transferase,Acute Coronary Syndrome,Non ST Elevation Acute Coronary Syndrome
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How to cite this article:

Magesh, V., B. Sasi Kumar and Arunachalam, P. 2016. A Study on Gamma Glutamyl transferase (GGT) in Non ST Elevation Acute Coronary Syndrome (NSTE-ACS) and its correlation with Angiographic severity and cardiac events.Int.J.Curr.Res.Aca.Rev. 4(2): 268-276
doi: http://dx.doi.org/10.20546/ijcrar.2016.402.030