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Abstract                 Volume:4  Issue-2  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

1, 2, 4-Triazole Scafolds: Recent Advances and Pharmacological  Applications
Anjali Thakur*, Puspraj S. Gupta, Parjanya kumar shukla, Amita verma and Prateek Pathak
Department of Pharmaceutical chemistry, Faculty of Health Sciences, Sam Higginbottom Institute of Agriculture, Technology & Sciences, Naini, Allahabad-211007, India
*Corresponding author
Abstract:

1,2,4-Triazole and its derivatives represent one of the most biologically active classes of compounds, possessing a wide spectrum of activities. The 1,2,4-triazole nucleus is associated with diverse pharmacological activities such as antibacterial, antifungal, hypoglycemic, antihypertensive, analgesic, anti-inflammatory, anti-tumor, anti-viral, urease inhibition and many other  properties. Either as single heterocyclic derivatives or in fusion with the other cycles, these heterocycle is emerging as the most explored center to obtain clinically significant compounds. In present study we explore the method of preparation, some recent advances and biological activities of 1,2,4-triazoles which give an idea about this moiety as potent medicinal agent for new drug discovery.

Keywords: Triazoles,1,2,4-triazoles,Heterocycle compounds, Antifungal, Antimicrobial
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How to cite this article:

Anjali Thakur, Puspraj S. Gupta, Parjanya kumar shukla, Amita verma and Prateek Pathak. 2016. 1, 2, 4-Triazole Scafolds : Recent Advances and Pharmacological  Applications.Int.J.Curr.Res.Aca.Rev. 4(2): 277-296
doi: http://dx.doi.org/10.20546/ijcrar.2016.402.031