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Abstract                 Volume:6  Issue-7  Year-2018          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
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Synthesis of Gold Nanoparticles Using Penicillium sp. and their Antibacterial Activity against Human Pathogens
Nigar Sulthana* and A. Rajanikanth
Department of Biotechnology, SPW Degree & PG College, Tirupati, A.P, India
*Corresponding author
Abstract:

This study was planned to obtain fungi from garden of SPW Degree and PG College, Tirupati with the extreme goal of producing antibacterial nanoparticles. Among 5 funguses isolated, an isolate coded as SPW-1 identified as Penicillium sp has produced nanoparticles extracellularly within 12 h. These nanoparticles were characterized by UV-Vis. Spectrophotometer, TEM, and FTIR analysis. Penicillium sp synthesized gold nanoparticles showed many interesting morphologies with a size of 4-20 nm. The presence and binding of proteins with nanoparticles was confirmed by FTIR study. Interestingly, the fungal derived gold nanoparticles exhibited superior antibacterial activity than the standard antibiotic, penicillin-G against E. coli and Bacillus cereus. Thus, the obtained results reveal that these antibacterial nanoparticles could be explored as promising candidates for a variety of biomedical and pharmaceutical applications.

Keywords: Soil fungi, Penicillium Sp, Gold nanoparticles (GNPs), Antibacterial activity
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How to cite this article:

Nigar Sulthana R. and Rajanikanth A. 2018. Synthesis of Gold Nanoparticles Using Penicillium sp. and their Antibacterial Activity against Human PathogensInt.J.Curr.Res.Aca.Rev. 6(7): 19-24
doi: https://doi.org/10.20546/ijcrar.2018.607.003