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International Journal of Current Research and Academic Review-e-iSSN - 2347 - 3215

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Abstract                 Volume:6  Issue-12  Year-2018          Original Research Articles

Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Antimicrobial Resistance in Pediatric Sepsis: A Study from a Tertiary Care Hospital in North India
Swati Sharma*, Anuj Sud and Beena Uppal
Department of Microbiology, Maulana Azad Medical College, New Delhi, India
*Corresponding author

Sepsis is a leading cause of mortality in children. However, there is limited data on the pathogens associated with sepsis in children in developing countries. 250 patients aged between 2 months to 5 years clinically suspected of sepsis were recruited in the study. Blood samples were collected from all patients at the time of admission for performing blood culture. Antimicrobial susceptibility pattern was studied using Vitek 2 system. Gram negative bacteria are more commonly associated with sepsis (66.7%) than Gram positive bacteria (33.3%). A higher degree of resistance was seen to fluoroquinolones (71.4%), amoxicillin + clavulanic acid (61.9%), cephalosporins (58.8%) and gentamicin (57.1%), among Gram negative bacteria and to penicillin (100%), gentamicin (57.1%), cephalosporins (57.1) and fluoroquinolones (50%) among Gram positive bacteria. Gram negative bacteria are the predominant agents of pediatric sepsis in developing countries. Antimicrobial resistance to gram negative isolates is rising.

Keywords: Antimicrobial resistance, Gram negative infection, Pediatric sepsis.
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How to cite this article:

Swati Sharmaa, Anuj Suda and Beena Uppal. 2018. Antimicrobial Resistance in Pediatric Sepsis: A Study from a Tertiary Care Hospital in North India.Int.J.Curr.Res.Aca.Rev. 6(12): 7-13
doi: https://doi.org/10.20546/ijcrar.2018.612.002