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Abstract                 Volume:4  Issue-3  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Protein Creatinine Ratio (PCR) from Random Urine Samples in Patients with Chronic Kidney Disease
P.T. Komala*
Department of Biochemistry, Meenakshi Medical College and Research Institute, Kanchipuram-631552, Tamil Nadu, India
*Corresponding author
Abstract:

The aims of this study was to assess the ability of Protein to Creatinine ratio from random urine samples to rule in or rule out proteinuria in patients with Chronic Kidney Disease. Chronic renal failure is a clinical syndrome resulting in the progressive loss of renal function.  The symptoms of chronic renal failure result not only from simple excretory failure but also from the onset of regulating failure, the kidney’s failure to regulate certain substances, such as sodium & water. Chronic kidney disease patients were selected on the basis of serum creatinine levels. In this study, we demonstrated that urinary creatinine very helpful for chronic renal failure. Collection of 24hr urine samples is cumbersome and prone to errors, hence analyte measurement in random urine is often proposed with correction for variation in urine flow rate by expressing results as a ratio to creatinine concentration. The tests are to be used for monitoring the level of proteinuria in established renal disease, they can then be used as surrogates for 24hr measurements

Keywords: Creatinine, Proteinuria, Chronic Kidney disease
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How to cite this article:

Komala, P.T., 2016. Protein Creatinine Ratio (PCR) from Random Urine Samples in Patients with Chronic Kidney Disease.Int.J.Curr.Res.Aca.Rev. 4(3): 170-177
doi: http://dx.doi.org/10.20546/ijcrar.2016.403.018