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Abstract                 Volume:4  Issue-4  Year-2016          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
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Formulation and Evaluation of Gel of Leaf Extract of Jasminum grandiflorum
Lincy Joseph1*, Mathew George2, Shweta Agrawal3 and Prabha Mathews1
1Department of pharmaceutical Chemistry, Pushpagiri College of Pharmacy, Thiruvalla, 689107, Kerala, India
2Department of Pharmacology, Pushpagiri College of Pharmacy, Thiruvalla, 689107, Kerala, India
3Department of Pharmacognosy, School of Pharmaceutical Sciences, Jaipur National University, Jaipur-302050, Rajasthan, India
*Corresponding author
Abstract:

Medicinal plants are used in the Ayurvedic and Unani System of medicine besides use of many plants in the folk remedies. Medicinal plants are used in different countries as sources of many potent and powerful medicines. Semi solid dosage form is advantageous in terms of its easy application, rapid formulation and ability to topically deliver a wide variety of drug molecules. Topical drug delivery gained popularity because it provides a largest surface area, avoids first pass effects and gastrointestinal irritation. Topical gel formulations provide a suitable delivery system, because they are less greasy, can be easily removed from skin and provide a successful approach in delivering combination products. In the present study gel was formulated from aqueous extracts of Jasminum grandiflorum, and evaluated its physical, chemical and biological properties. The physical evaluation of formulated gel for parameters like pH, refractive index, specific gravity complies with the standard specification. The chemical investigation of gel showed the presence of various phytoconstituents like phytosterol, phenols, tannins, flavanoids, alkaloids,  carbohydrates, saponins terpenes. The biological evaluation was done by testing the gel against various microorganisms and was found most effective against S aureus.

Keywords: Jasminum grandiflorum, Formulation of gel, Evaluation of gel, Screening for antibacterial activity.
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How to cite this article:

Lincy Joseph, Mathew George, Shweta Agrawal and Prabha Mathews. 2016. Formulation and Evaluation of Gel of Leaf Extract of Jasminum grandifloram. Int.J.Curr.Res.Aca.Rev. 4(4): 68-73
doi: http://dx.doi.org/10.20546/ijcrar.2016.404.008