Abstract            Volume:14  Issue-10  Year-2026         Original Research Articles

Online ISSN : 2347 - 3215 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcret@gmail.com

A 5-week study evaluated the efficacy of a hepatic product on growth, nutrient retention and carcass traits of 240-day-old Vencobb-430Y broiler chicks under hepatic toxin induced conditions. Birds were randomly allotted to four treatments (4 replicates/15 birds each): A (Control; basal diet), B (Negative control; CCL₄ liver challenger @1ml/kg body weight orally at every 3^rd day from 15^th to 28^th days of trial), C (As B + test liver tonic @ 2 ml/L water), and D (As B + standard liver tonic @ 5,10 and 20 ml/100 birds at pre-starter, starter and finisher phases, respectively). All birds were floor-reared with ad libitum basal feed (BIS 2007) and routine vaccinations. Oral CCL₄ challenge significantly (p<0.05) depressed final body weight (2033.13 g) and overall weight gain (1989.26 g) in group B compared to control group A (2233.06 g and 2189.26 g). Supplementation of test liver product (Group C) effectively counteracted hepatotoxicity, restoring final weight (2158.87 g) and total gain (2115.54 g) to levels comparable (p>0.05) to control A and numerically superior to standard liver tonic group D (2082.50 g). Feed consumption remained non-significant across groups, but overall FCR significantly (p<0.05) worsened in group B (1.62) relative to A (1.51). Test liver tonic supplementation (Group C) improved FCR (1.54), outperforming group D (1.56) numerically. Furthermore, the test liver tonic restored CCl₄ induced numerical drops in dry matter digestibility (75.6%), nitrogen retention (70.34%), crude fibre (48.74%), and ether extract digestibility (90.54%) back toward baseline levels. However, the digestibility difference of different nutrients in different groups remained non-significant (p>0.05). In conclusion, the test liver tonic @ 2 ml/L drinking water successfully protected against toxin based (CCl₄-induced) hepatic damage, preserving growth performance, feed efficiency, and nutrient digestibility in broilers.

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