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Abstract                 Volume:9  Issue-9  Year-2021          Original Research Articles


Online ISSN : 2347 - 3215
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcret@gmail.com

Hyperendemicity and Recrudescence of Dengue Activity Reported from a Tertiary Care Hospital in NCR Region
R. Tomar*, D. Bisht and V. Goel
Department of Microbiology, Santosh Medical College & Hospital, Ghaziabad, Uttar Pradesh, India
*Corresponding author
Abstract:

The objective of this research was to investigate the presence of hyperendemicity and recrudescence activity of dengue by using Real Time RT-PCR for dengue serotyping. A total of 246 clinically suspected cases of dengue were selected based on WHO 2009 dengue case classification. Acute phase blood samples were tested for NS1 antigen, IgM and IgG antibody and samples positive by one of the parameters: NS1 Ag and/or IgM Ab/IgG Ab were further subjected to Real time RT-PCR. Of the 246 clinically suspected cases of Dengue, 68 (27.6%) were positive for NS1 Ag and/or IgM Ab/IgG Ab and of these, 30 (44%) samples were positive by Real time RT-PCR. All the four dengue serotypes were found to co-circulate in this region, however no sample harboured more than one serotype. Co-circulation of all four dengue serotypes in the studied region emphasises the need of molecular monitoring of circulating DENV serotypes.

Keywords: Dengue serotypes, Co-circulation, Hyperendemicity, Recrudescence, Concurrent Infection.
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How to cite this article:

Tomar, R., D. Bisht and Goel, V. 2021. Hyperendemicity and Recrudescence of Dengue Activity Reported from A Tertiary Care Hospital in NCR Region.Int.J.Curr.Res.Aca.Rev. 9(9): 65-71
doi: https://doi.org/10.20546/ijcrar.2021.909.007